Pharyngo-laryngeal histoplasmosis in an immunocompromised child—a case report

Abstract Background Histoplasmosis is an endemic granulomatous fungal infection which rarely infects the larynx; less than 100 cases have been reported in medical literature till date. Case presentation A 6-year-old female child, a diagnosed case of B cell acute lymphoblastic leukemia since past 2 years and on chemotherapy, presented with hoarseness dysphagia months. Direct laryngoscopy revealed granular appearance posterior pharyngeal wall supra-glottic larynx. Histopathological examination bone marrow aspiration confirmed diagnosis disseminated histoplasmosis. Conclusions Pharyngo-laryngeal histoplasmosis should be considered differential immunocompromised patient presenting persistent hoarseness.